Defense Priorities Defense Priorities
  • Policy Topics
    • Israel-Iran
    • Ukraine-Russia
    • NATO
    • China
    • Syria
  • Research
    • Briefs
    • Explainers
    • Reports
  • Programs
    • Grand Strategy Program
    • Military Analysis Program
    • Asia Program
    • Middle East Program
  • Experts
  • Events
  • Media
  • About
    • Mission & Vision
    • People
    • Jobs
    • Contact
  • Donate
Select Page
Home / Iran / Iranian supreme leader’s options are limited in war with Israel
Iran, Israel, Israel‑Iran, Middle East

June 16, 2025

Iranian supreme leader’s options are limited in war with Israel

By Daniel DePetris

Iran’s supreme leader, Ayatollah Ali Khamenei, and the Islamic regime he has led for more than 35 years now face their biggest test since the eight-year war with Iraq in the 1980s.

Since Thursday night, Iran has been bombarded by intense Israeli airstrikes that show no signs of abating anytime soon. In connection with the Israeli air campaign, the Mossad, Israel’s foreign intelligence service, has been operating on Iranian soil and targeting senior Iranian nuclear scientists and military officers in an attempt to shatter the Iranian military’s chain of command. Iran’s armed forces chief, the intelligence chief of the elite Islamic Revolutionary Guard Corps (IRGC) and the supreme leader’s senior foreign policy adviser have all been killed. Khamenei himself was in Israel’s crosshairs, although President Donald Trump dissuaded the Israelis from assassinating him, fearing an even deeper escalation.

Over the last 72 hours, Israeli Prime Minister Benjamin Netanyahu has stepped up the air campaign by striking sites such as the South Pars natural gas field and refineries on the outskirts of Tehran. Netanyahu seems to be ever more enamored with going beyond Israel’s original objective, telling Fox News last weekend that regime change in Tehran could very well be the ultimate result.

Read at Chicago Tribune

Author

Photo of Daniel DePetris

Daniel
DePetris

Fellow

Defense Priorities

More on Middle East

op-edGrand strategy, Military analysis

America needs to take better care of its military

By Dan Caldwell

July 28, 2025

op-edGrand strategy, Iran, Israel, Middle East

There are no more reasons for U.S. presence in Middle East

By William Walldorf

July 28, 2025

op-edIsrael‑Iran, Iran, Israel, Middle East

Donald Trump and Benjamin Netanyahu don’t have the same goals

By Daniel DePetris

July 22, 2025

op-edIsrael‑Iran, Iran, Israel, Middle East

What comes next in U.S.-Iran talks?

By Alexander Langlois

July 18, 2025

op-edSyria, Israel, Middle East

Israel’s calculus on Syria

By Daniel DePetris and Rajan Menon

July 17, 2025

In the mediaIsrael‑Iran, Middle East

New assessment finds site at focus of U.S. strikes in Iran badly damaged

Featuring Rosemary Kelanic

July 17, 2025

Events on Iran

See All Events
virtualMiddle East, Basing and force posture, Diplomacy, Houthis, Iran, Iraq, Israel, Israel‑Hamas, Military analysis, Syria

Past Virtual Event: Trump in the Middle East: Impacts, implications, and alternatives

May 16, 2025
virtualHouthis, Iran, Israel‑Hamas, Middle East, Yemen

Past Virtual Event: Houthi conundrum: defend, degrade, or defer

March 28, 2024
virtualMiddle East, Iran, Israel‑Hamas, Israel‑Iran, Syria, Yemen

Past Virtual Event: Keeping the U.S. out of war in the Middle East

January 16, 2024

Receive expert foreign policy analysis

Join the hub of realism and restraint

Expert updates and analysis to enhance your understanding of vital U.S. national security issues

Defense Priority Mono Logo

Our mission is to inform citizens, thought leaders, and policymakers of the importance of a strong, dynamic military—used more judiciously to protect America’s narrowly defined national interests—and promote a realistic grand strategy prioritizing restraint, diplomacy, and free trade to ensure U.S. security.

  • About
  • For Media
  • Jobs
  • Donate
  • Privacy Policy
  • Terms and Conditions
  • Contact
© 2025 Defense Priorities All Right Reserved